in Daily Dose, Data, Featured, News, Origination The number of single-family homes built-for-rent declined at the start of 2019, according to the latest data from the National Association of Homebuilders (NAHB) and the Census Bureau. The Census Bureau’s Quarterly Starts and Completions by Purpose and Design report indicates that there were 5,000 single-family built-for-rent starts for the first quarter of 2019, below the 6,000 estimated for the start of 2018. Over the last four quarters, 42,000 such homes began construction.The NAHB notes that these quarter-to-quarter fluctuations were not statistically significant. The current four-quarter moving average of market share (4.8%) remains higher than the recent historical average of 2.7% (1992-2012) but is down from the 5.8% reading registered at the start of 2013. Though built-for-rent single-family rentals have been on the decline, the overall single-family rental market has been on the rise. The market for single-family rental (SFR) securitizations continued to grow month over month. It increased to 4.7% in March from 4.2%, according to the latest Morningstar Credit Ratings report on the SFR market.The report indicated that the average vacancy rate had declined overall to 4% in March—the lowest since May 2018.The average retention rate for expiring leases also dropped to 78.9% in February, the latest month available, from 80.4% in January.Looking at single borrower performance, the report found that lease expirations had increased to 6.6% in March, up from 6% in February. Among the securitizations analyzed by Morningstar, AH4R 2015-SFR1 had the highest lease expirations at 8.3%, up from 7.6% in February. On the other hand, PRD 2018-SFR1 had the lowest percentage of lease expirations at 2.7% followed by PRD 2015-SFR3 at 4.4%.Among the securitized properties, the report said that rent gains from securitized properties in March trailed rent gains for three-bedroom properties. Additionally, the rent change for three-bedroom properties declined slightly to 5.6% from 6% in February. The rent for four-bedroom properties remained unchanged during the period.Rent growth for vacant-to-occupied properties increased to 3.9% from 2.5%, the report indicated. Share Analyzing Single-Family Rental Construction May 17, 2019 471 Views rentals Single-Family 2019-05-17 Seth Welborn
Subscription video-on-demand service Cirkus has struck a deal with Scandi telco TeliaSonera and will launch on its pay TV services in Sweden and Finland.The agreement between UK-based Cirkus and TeliaSonera means the SVOD service will launch on its pay service in Finland this autumn and in Sweden in early 2015. The service is already carried on Com Hem and Boxer in Sweden.UK broadcaster ITV recently bought into Cirkus, which positions itself as a way for pay TV operators to take on the threat from OTT services with a low-cost SVOD service.It offers on-demand access to shows from ITV Studios and other distributors including All3Media International, BBC Worldwide and Endemol Worldwide Distribution.Cirkus said further deals with pay TV operators will be announced shortly. read more
Dear Reader,Vedran Vuk here, filling in for David Galland. David’s schedule is packed with events down in Argentina including the Harvest Celebration at La Estancia de Cafayate, so I’ll be steering the ship for the next few weeks. First today, we’ll have an article from Dennis Miller on when to trust your instincts on your gold holdings. Then, I’ll address the age-old question, “How come you could raise a family on a single paycheck back in the day and now you can’t?” I’ll give you one big reason why, as well as a way to make that old standard a reality again.Also, make sure to check out Dennis’ recent interview on Real Money Radio with David Holland (to get right into the part with Dennis, skip about the first five minutes of the program). Dennis really knocked this interview out of the park. He tells his retirement story of having a secure nest egg of CDs ripped out from under him, thanks to the 2008 crisis.Not only does Dennis often talk about his experience in retirement, we’ve also been doing really well in the Money Forever portfolio. In Dennis’ article titled Twelve Tips for Buying Dividend-Paying Stocks, item number ten was choosing stocks with a history of increasing dividends. Looking at our current portfolio, five out of six dividend-paying stocks have increased their dividend since becoming a part of our portfolio. The CFO of the sixth company has said a dividend increase is planned for this year, but hasn’t set a specific date and amount.These dividend increases ranged from an incremental hike of 2% to one company raising its dividend by 150%. To be fair, that company had the lowest dividend yield – 0.8% – of the six. We primarily recommended it for reasons other than its yield, but we’re more than happy to be now collecting 2% on it. If you want to check out our portfolio as well as advice on planning for retirement, try out a trial subscription of Money Forever.Before we get started today, I also want to mention the upcoming Liberty Forum at St. Kitts in the West Indies, May 15-18. Doug Casey will be the feature speaker at the forum and will be joined by Jeff Clark, Bud Conrad, and Terry Coxon as well. Many Casey Research friends will also be attending, including Jeff Berwick, Rick Rule, and my good friend Doug French. The West Indies and a panel full of excellent speakers – sounds like a great time to me. Now, let’s get to Dennis’ take on trusting your instincts when it comes to gold.Trust Your Instincts on GoldBy Dennis Miller, Editor of Money ForeverI recall a terrifying experience years ago. It was my last flight of the year, and I was headed home for Christmas. The plane was speeding down the runway to take off, when the pilot suddenly reversed thrust and slammed on the brakes; the plane shook like I have never experienced before as the pilot aborted the takeoff. As we stopped mere feet from the end of the runway and caught our breath, the pilot came on the intercom and announced, “I’m sorry to frighten you, ladies and gentlemen. I have been flying for many years. There was nothing on our instrument panel that says we have any kind of problem. It just did not feel right, and I want to have some things checked out before we go vaulting into the air.”We taxied back to the gate and several mechanics descended on the plane. Within ten minutes they made the announcement that the flight had been canceled due to mechanical difficulties. As I exited, I stuck my head in the cockpit door and exclaimed, “Captain, I will fly with you any time – thank you! I hope you have a wonderful Christmas season.” As a seasoned traveler, it was probably the only time in my life that I was happy about having a flight canceled.It just doesn’t feel rightAs of this moment, the business columns are blaring headlines about the Dow hitting a record high. At the same time, gold and gold stocks have been taking a beating. If you are like a lot of us at Casey Research and have sizeable positions in gold and silver, it can certainly be a test of courage and patience.At times like this, it seems appropriate to review why we made certain decisions in light of new facts. Have things changed? Is it time to adjust our holdings?As luck would have it, Federal Reserve Vice Chairman Janet Yellen sheds some light on the subject. Bloomberg’s recent headline, Yellen Says Fed Should Press on With QE Amid Limited Risk, sums it up well. Basically she reiterated that the Federal Reserve will keep on purchasing $85 billion in government debt for the foreseeable future. OK, no changes here, folks; we will continue to spend money we don’t have, and the Fed will cover us.The same day I read about Ms. Yellen, the March issue of BIG GOLD hit my inbox. In the introduction, our own Jeff Clark has this to say about the situation (italics his):“[T]he fundamental drivers for investing in gold have not changed. If they had, then we should sell, but clearly they have not. This is a short-term correction within a secular trend, despite what some may proclaim.The primary impetus for a sustained gold bull market is that government debt is a structural problem, in the US and across the globe. Most of it will never be paid – and more piles up every day, to the tune of tens of billions of dollars. The economies of the world’s indebted nations are not and cannot grow fast enough to pay off the debt (GDP shrunk [sic] last quarter in the US, the Eurozone, and Japan), and outright default or restructuring (i.e., a “soft default”) isn’t an option. The only politically acceptable way out is for government to create the money to service the debt and pay its bills, inflation be damned.This default-by-inflation has been repeatedly employed by governments throughout history. We don’t see a different outcome this time.The Fed has said it wants inflation – and we’re sure it’ll get what it wants. No forecast comes with a guarantee, but it seems virtually certain that central banks will continue to print money. Since those currencies can’t get “unprinted,” they’ll eventually enter the system and fuel double-digit rates of price inflation. When that process starts to unfold, gold and silver will respond, as they dependably have throughout history.”And of course I catch a quick glimpse of talking heads on CNBC enthusiastically discussing the Dow. One of the experts makes the snide remark that all the gold nuts talking about Zimbabwe need to step aside, because they just want to make some money.Much like the pilot, my intuition is sending me a message – I am trying to figure out my emotional conflict at the moment. I know I’m heavily in the market with my share of metal and stocks, because I have no choice. They took away our interest income. Most all of my peers feel the same way. We are not heavily in the market because we want to be; we really have little other choice.Maybe the Dow did hit a high, but it feels more like the Great Depression than the roaring ’20s. Unemployment is through the roof, record numbers of people are on food stamps, and we see study after study about our net worth decreasing rapidly.So here is my current thinkingLet the talking heads at CNBC continue to make fun of me. I think we can do two things at once: make some money and do everything we can to protect ourselves against a possible Zimbabwe moment.There are certain potential catastrophes that can be so threatening we must take steps to insure ourselves even though the probability of one actually occurring is slim. I cannot put my life savings and my family at risk by trivializing the dangers which are potentially on the horizon.While CNBC may want to pooh-pooh the probability of something similar happening in our country, we all know that creating massive amounts of currency out of thin air always results in the currency collapsing or being revalued. A prudent investor (particularly one on either side of the cusp of retirement) would do well to take out some insurance. That is generally done by investing in metal, farmland, and other forms of hard assets.In the same Bloomberg article quoting Ms. Yellen, there is another clue for us: “Kansas City Fed President Esther George has warned that prices of some farm land have hit ‘historically high levels.’” I wonder if the CNBC folks feel that is a mere coincidence.In the fall of 2011, I attended the Casey Summit, which featured three speakers who had lived through hyperinflation in their home countries. They shared their personal experiences with us.All three speakers went through very similar cycles. All said inflation was rising and then it spiked to astronomical proportions.The following are a couple of slides used by the speaker from Yugoslavia. Note the last line that indicated that during its hyperinflation, on average every 1.4 days prices doubled. The presenter showed a 500-billion denominated bill, which had the same purchasing power as a 500 bill was worth just 24 months earlier. His slides documented the hyperinflation, starting at 5.00 and building up to 500 billion.Can this happen in the United States? Are we immune from the natural laws of economics?We see inflation on the rise in the US and know our government is not telling us the truth about it. We have discussed the record debt and Federal Reserve spending until we are blue in the face.Here is my personal bottom lineI have yet to see anyone present any logical economic premise that concludes that our country will not eventually see a currency collapse. Many have put us down, called us “gold nuts” and the like, and trivialized our concerns. Just show me the facts.I see several other clues that reinforce my concerns. Throughout history thousands of currencies have collapsed, but precious metals hold their value. It should come as no surprise to learn that over the last few years China, Russia, and many central banks are stockpiling gold. Germany and Venezuela just announced they are bringing their gold back to their shores. Not wanting to start a panic or gold rush, they played it down by saying they just feel it is easier having their metal inside their own borders. It sits in a lump and earns no interest, so there must be a good reason why they are going through all that effort and expense.At Casey Research, we have regular editors’ conferences. The subject of the last two was precious metals and the direction of the market. If I may summarize, we came to several conclusions. We may be in for a rough ride in the short term; however, the fundamental reasons for owing gold and silver have not changed. If anything, the reasons to own gold and silver are more evident than ever before. At the end of the day, none of us is selling, and we are going to be ever alert for some terrific buying opportunities.Sure, all the contraptions on the airplane might be telling us everything is just fine: the Dow reaches new highs; unemployment slowly drops; and cheap credit is endless. But as experienced pilots, we’re reading into the market beyond what the gauges are saying. That’s the sort of insight that can mean the difference between and a crash landing and a takeoff for the value of your portfolio.Living on Two Paychecks or on Too Many Expectations?By Vedran Vuk, Senior Research AnalystIn a discussion with a good friend, he asked me, “How come in the 1950s, you could support a family on a single paycheck, but my wife and I both have to work to make ends meet?” I’ve heard this question so many times, and people give innumerable reasons, from the Fed’s inflationary policies to the lack of decent-paying manufacturing jobs. Usually, the explanations suggest macroeconomic shifts and major policy changes. And sure, some of those explanations are a part of it, but what’s often not considered is the expense side of the equation.If we’re going to compare ourselves to a 1950s standard, we have to ask whether our spending is similar to the 1950s. If we strip out all of our unnecessary modern expenditures and make an apples-to-apples comparison, most of us probably could live on a single paycheck. The problem is not that our standard of living has gotten worse – it’s that our expectations have far outgrown the reality of most paychecks.Let’s first start with some modern inventions which are ultimately conveniences. For example, there’s your cellphone bill and monthly high-speed Internet connection. These are important tools in the modern age, but you could live without them. Then, think of the innumerable gadgets which occupy most of our homes, from iPads and iPods to laptops to flat-screen TVs to Xbox game consoles, and so on. Unless you really need these devices for your work, it’s hard to argue that one couldn’t live without them. People in the 1950s survived without them – and so could you.Let’s move it up a step to some bigger expenditures. According to the Department of Energy, in 1950 there were 323 vehicles per thousand people in the US. In 2010, there were 811 vehicles per thousand people. Today, every member of the family has a car, if not one to spare – and we’re not talking old junkers, but pretty nice cars. I often ask myself, “How come I earn more than the US median, yet it seems like 75% of people around me are driving nicer cars?”Now let’s take it one step further to the really big expenses. Take a drive down to a middle-class neighborhood built in the 1940s and ’50s. What you’ll see are very modest homes – one-story buildings with a small bedroom for the parents and two to three closet-sized bedrooms for the kids, a living room, a kitchen, and a dining room. Depending on how lucky you were, there may have been two bathrooms instead of one. This cookie-cutter formula spanned the country. The houses weren’t that pretty or incredible, but they got the job of raising a family done.After your drive to that part of town, cruise into a middle-class subdivision built in the last ten or twenty years – it’s a completely different picture. Every house is either a McMansion or made to resemble a smaller version of a McMansion. The kids’ bedrooms in these things are bigger than my whole first apartment. Let’s not even mention the size of the master bedroom; and of course nearly every bedroom has its own bath. Don’t forget the additional rooms, such as “the playroom.”What’s considered a middle-class lifestyle today isn’t even close to the middle class of the 1950s. Add up all of these things: the gadgets, the cellphone and Internet bills, the brand-new cars for the whole family, and the mini-mansions – it’s a ton of money that the last generation wasn’t spending. When someone lives this sort of lifestyle and wonders, “Jeez, why do my wife and I both have to work?,” my answer is, “Well duh, genius. Of course both of you have to work. Look at your lifestyle.” If you lived more modestly and within your means, the necessity of two paychecks will not seem so set in stone.Now, I’m not suggesting that everyone should live a miserly, monastic life. I’m sure that if we could send cellphones back into the past, people in the 1950s would buy them too. What I’m suggesting is simply to take a second and reconsider what really makes us happy and fulfills our needs. Did people in the 1950s live unfulfilled lives without three iPads and a McMansion?This reevaluation of our spending priorities is especially important for retirement planning. Recently, I helped my dad crunch the numbers for his retirement plan. I have to commend him for working extra hard lately to play catch-up with his retirement. After crunching the numbers, I told my dad, “I have some really good news. If you were willing to live modestly, you could retire next year. If you moved back to Croatia, you could even live very well over there. But to reach the sort of retirement income that you have in mind, you’ll have to work at least ten more years.” He said, “Well, I guess I’ll have to work ten more years.”There’s nothing truly wrong with his answer. If he wants to work longer to earn more, that’s up to him. However, at some point this sort of perspective makes you a prisoner of your own expectations. With an investment-newsletter subscription, we can recommend investments to strengthen your portfolio. While managing your investments is important, what doesn’t cost a penny is adjusting expectations. It’s a lot harder to earn 30% returns than to downsize to a lifestyle that might require only 8% returns. However, if your expectations are through the roof, then 40% returns and another 20 working years won’t be enough to satisfy your desires.When it comes to retirement, if you don’t limit your expectations and put them into check, one of two things will happen. Either you will have to keep slaving away to bring in more income to fulfill your desires, or you’ll fail to earn enough, and you’ll always feel jilted and empty. Even if the first option works out, someone will always have a bigger yacht or house. At retirement, it’s time to stop keeping up with Joneses (and stopping well before then can help you hold on to more of your hard-earned money). The combination of a fixed income and endless desires is a guaranteed route to misery and unhappiness.Maybe you don’t need to retire in a McMansion or have three houses in retirement or drive the newest Corvette. People have lived very well on more modest incomes long before the current era of unlimited spending and endless expectations. Maybe – just maybe – the problem in our modern society is not a paycheck which is too small, but rather expectations which are too big.Friday FunniesHere’s a very funny spoof of the Pentagon’s worries about the sequester cuts from The New Yorker:Pentagon: Cuts Could Hamper Ability To Invade Countries For No ReasonPosted by Andy BorowitzWASHINGTON (The Borowitz Report) – The spending cuts mandated by the sequester may hamper the United States’s ability to invade countries for absolutely no reason, a Pentagon spokesman warned today.The Pentagon made this gloomy assessment amid widespread fears that the nation’s ability to wage totally optional wars based on bogus pretexts may be in peril.“Historically, the United States has stood ready and able to throw billions of dollars at a military campaign with no clear rationale or well-defined objective,” said spokesman Harland Dorrinson. “Our capacity to wage war willy-nilly is now in jeopardy.”In the past, Mr. Dorrinson said, the Pentagon has had the resources to fight three meaningless and completely random wars at any given time, “but now in our planning meetings we are cutting that number back to two.”Sen. Lindsey Graham (R S.C.) agreed about the catastrophic effects of the Pentagon cuts, telling reporters, “The ability of the United States to project its military power in an arbitrary and totally capricious way must never be compromised.”The cuts are already being felt in a tangible way at the Pentagon, which today cancelled an order for a nine-thousand-dollar pen.Here’s some more spoof news, but from the almost-too-funny spoof site The Onion. These stories are just overflowing with sarcasm. First, on the topic of the American Airlines and US Airways merger:American Airlines, US Airways Merge To Form World’s Largest InconvenienceFORT WORTH, TX – American Airlines and US Airways stunned the aviation industry Thursday upon announcing the two air travel titans have combined in an $11 billion merger that sources say will unite the industry powerhouses into the world’s largest and most complete pain in the ass. “Today we embark upon a bold and unprecedented new venture into customer frustration,” American CEO Tom Horton said of the historic alliance, which analysts predict will pose an immediate threat to rivals United and Delta in the air travel industry’s key areas of flight delays, lost luggage, and useless customer service. “When you take our general administrative incompetence and integrate it with our new partner’s long-proven inability to meet flyers’ needs in any capacity, you’ve got a brilliant new model in passenger aggravation and travel plan disruption. This truly will be the leading entity in the hassle industry.” Horton also confirmed the new multi-billion-dollar headache hopes to f*** up more than 4,000 flights a day.Here’s one on AIG:AIG Nearly Blows All The Goodwill Built Up By Wall Street In Recent YearsNEW YORK – Wall Street narrowly dodged a devastating blow to its reputation Wednesday as insurance giant American International Group seriously considered suing the federal government over the terms of its 2008 bailout, a move that experts agreed would have destroyed the tremendous amount of trust and affection the U.S. populace currently feels toward big banks.Sources said if AIG had decided to join a $25 billion lawsuit over the assistance it received from from [sic] taxpayers following a devastating economic crisis for which no one has been held accountable, then citizens who now feel a deep fondness for the nation’s financial institutions may have become outright angry with them instead.“Wall Street really won me over in 2008 when it veered toward total collapse after years of predatory lending practices,” said Jessica Woodward, 37, a Cincinnati-based software engineer. “And the banks definitely had a special place in my heart after they continued foreclosing on homeowners they shouldn’t have loaned money to in the first place.”“But if AIG had gone ahead with this lawsuit – well, I’m not sure that’s something I could have turned a blind eye to,” she added.Many Americans echoed Woodward’s disapproval, saying it would have been “terribly unfortunate” if the company had gone ahead with its plan to sue the government just a few years after receiving a $182 billion bailout package, considering all the work Wall Street had done to rebuild its good name by granting top-ranking officials obscene bonuses, systematically lying to investors, and failing to reform its practices.“Thankfully, AIG has avoided any action that might have sullied the public’s view of the financial industry as a whole,” said Sam Kerr, a father of three in Boise, ID. “Their decision today showed a tremendous amount of respect for the American taxpayer.”“Honestly, they deserve a round of applause for this,” he added.This last one on the sequestration is a little longer; so I’ll just post an excerpt. Click on the title for the whole thing:Obama, Congress Must Reach Deal On Budget By March 1, And Then April 1, And Then April 20, And Then April 28, And Then May 1“Experts say that without reaching a deal this Friday, the automatic $85 billion reduction in government spending will immediately slow the U.S. economy and impact thousands of middle-class citizens. Officials said the same exact thing will happen next month, the month after that, and the month after that if Obama and Congress fail to meet deadlines created by the preceding, incomplete deals.“If the president and Congress are unable to reach a grand bargain by Mar. 1, what they will likely do is reach a set of 100 or so smaller bargains, all with their own deadlines, and all of which could potentially plunge the U.S. economy into a recession,” said Princeton economics professor Marshall Kahn. “So, the Mar. 1 deadline is absolutely crucial. Just like the one next month will be. And the 12 deadlines in May. And the bi-daily deadlines that will kick in during the summer.”“Based on the way the president and Congress deal with one another,” Kahn added, “in 2014, there will need to be 4,562 budget deals.”That’s it for today. Thank you for reading and subscribing to the Casey Daily Dispatch. See you next week.Vedran VukCasey Senior Analyst read more
I woke up today to this video—a Taco Bell ad, if you can believe it—that I found posted on one of my regular sites. Please watch it. I think there is a reason why images of this kind are resonating with more and more people. When I was a boy, we would look at something like this and think “Soviet Russia.” Not so much anymore… aside, perhaps, from the film’s background setting. Just a few minutes later, I opened an email from a friend, linking to a speech delivered a few days ago in Toronto. It was delivered by a young author named Sofi Oksanen (I’m told she’s terrific), commemorating the 1949 Baltic Deportations. As I went through the speech, I was struck by the fact that dominated people, irrespective of where and when, go through the same things. We tend to think of domination in very large, overt terms, but the truth is that domination rests on a foundation of attitudes and expectations. External domination requires the support of internal domination. Hard, soft, or otherwise, domination involves the same themes, over and over. So, here are some passages from Ms. Oksanen’s speech, and the thoughts that they spawned in me: The Soviet system depended on the fact that people had learned not to give voice publicly to things that were unfavorable to the system. Have you ever noticed that when people speak badly of the IRS or the NSA, they lower their voices? That is precisely the same thing that happened under the USSR. There is zero difference. Did this happen more commonly under Stalin? Perhaps, but, more often than not, that’s just an excuse to ignore the subject. We may as well say, If it was worse under Stalin, then we’re free. And if that’s a valid statement, the tortured victims of the Soviet gulags should have been saying, It’s worse in Cambodia under Pol Pot. So, we’re free. And perhaps they were. Domination rests on statements such as these. And every time we lower our voices, we affirm the fact that our culture is dominated by brutes. Those who expressed improper opinions risked being denied entry to the Soviet Union where our relatives were still living… We were under constant threat that we would never again be allowed to step inside the borders of the Soviet Union, never again see our relatives. Have you noticed all the exit-tax laws that have passed in recent years? I can tell you that the people who’ve thought about running away have noticed them. You can now be denied reentry to the United States for any number of reasons. There are tax reasons, of course, but there is also a universal reason—the No Fly List. Piss off the dominators and you won’t be allowed to see your relatives ever again. And how, precisely, does one get on or off the No Fly List? Shall we say, Well, it isn’t being used very much like that? First of all, how would you know? Because you didn’t hear it on CBS News? And shall we really fall back on If it’s worse somewhere else, we’re free? Censorship… did not exist officially in the Soviet Union, but was masked as editorial recommendations. Think that isn’t the case here? Then start talking about 9/11 being an inside job, and see what happens to you. Now, I’m not sure that the “inside job” folks are right, but shouldn’t they be able to voice their opinions without being publicly shamed? “Conspiracy theory” is a term that is used to dominate thinking. And, sadly, it’s used mostly by the dominated, upon the dominated. “Free speech” sometimes protects individuals from hard domination. Soft domination, however, represses speech just as well. Again: Try playing “9/11 Truther” at a cocktail party some time. See what happens. The disconnect between the personal and the official was quite wearing, and it forced people to develop layered personalities, double-identities. I hear this all the time. People play “good, obedient boys and girls” when dealing with dominators, then do their best to avoid their predations. One of my friends dubbed this “the bifurcated life,” and he’s right. And it’s not especially good for us… not that we’re left many good choices. Finland, whose school textbooks had to have Moscow’s approval. This is standard these days, and has been for a long time. Textbooks are paid for by governments; therefore, they will never make governments look bad. Whether those government offices are near or far (more and more, the far ones dictate the content of textbooks) really doesn’t matter: Whoever pays will be supported. Memory also had to be rebuilt, biographies had to be collected and archived, a foundation for new research and history writing had to be created. I’m half tempted to use that as a catch phrase for my newsletter. Citizens of such nations… hold in their minds iconic images of their history and their tragedies. They find it difficult to grasp or imagine what kind of people they would be if they had grown up in another kind of reality. This is a serious problem for those who haven’t lived abroad. Trust that revealing private experiences or opinions does not get you in trouble. Trust that it does not lead to a psychiatric ward, where people holding opinions inconvenient to the state would be sent in a country in which anti-Soviet thoughts were literally a sign of mental disorder. I suspect that most people still don’t know the story of Brandon Raub. If you don’t, please read about it. These things are happening, in America… and they don’t make the evening news. It’s true, however, that such evils aren’t universal: this type of hard domination isn’t everywhere. For example, a few months ago, I attended a show trial in New York. The same actions, in a less rich, polished setting, would very nicely have fit the model of the 1930s Soviet Show Trial. But a couple of months before that, I was testifying in a fair trial in the Midwest, conducted by a sincere, honest judge. The difference between the two trials was political importance. And that brings to mind a Saul Bellow quote from several decades ago: For the first time in history, the human species as a whole has gone into politics. Everyone is in the act, and there is no telling what may come of it. Having the benefit of time that Mr. Bellow didn’t, I’ll tell you what comes out of it: rigged textbooks, political show trials, and censorship enforced by the censored. Ms. Oksanen continues: Countries who after getting out from under their occupiers have managed to create a free press. These days, we call the free press “Alternative Media.” But Alternative Media is under attack already. The dominators don’t like it, and they’ve been quite unrestrained for more than a decade. A large portion of the populace all but worships their violence. What reason would they have to pull back? Finally, here’s a quote that Ms. Oksanen included in her speech, originally from Tzvetan Todorov: The enemy is the great justifier of terror and a totalitarian state cannot live without enemies. If there aren’t any enemies, they must be invented. Something to think about, in my opinion. In The End… In the end, whether hard, soft, or otherwise, the evils of oppression in this world can always be traced back to domination. We must remember that the most dangerous of all dominations are not the ugliest and scariest; they’re the ones that seem normal to us… that can even seem essential to us. A Free-Man’s Take is written by lifestyle capitalist, author, and freedom advocate Paul Rosenberg. You can get much more from Paul in his unique monthly newsletter, Free-Man’s Perspective. read more
When you talk about traditional Scandinavian foods, you end up talking about porridge. In a cold climate, only certain grains could thrive — namely barley and oats. Their warm mush was a building block of early Nordic foodways, and is still a staple.Now, an everyday bowl of plain old grain mush hardly sounds controversial. But in the middle of the 19th century, Norway was gripped with a series of public debates that later became known as the Norwegian Porridge Feud. Really.Before we get into the debate, let’s talk porridge itself.”Porridge has been one of the fundaments of Scandinavian food culture from prehistoric times until the 20th century,” writes Henry Notaker in his book Food Culture in Scandinavia. “In some areas it was served two or three times a day, eventually as a thinner soup, or gruel.”Porridge was so important that there were special exemptions allowing people to cook it on religious holidays, even when other forms of work were banned.Traditionally, Norwegians would take flour or grits of oats or barley (rice if they were fancier), and simmer it up with water to make a gruel. Then, at the end, cooks would stir in an additional measure of flour to finish the pot. And when we’re talking Norwegian cooks, we’re talking about women.But in 1864, Peter Christen Asbjørnsen, writing under the pleasant-sounding pseudonum Clemens Bonifacius (“the gentle helper”), published a cookbook called Fornuftig Madstel (Sensible Cookery) which argued that the flour stirred in at the end was a misguided waste. Asbjørnsen maintained this uncooked flour went straight through the body without being used. He saw this not only as a loss to the farmer, but a loss to the economy of the country as a whole.Even before this bold claim was made, culinary ethnologists Astri Riddervold and Andreas Ropeid say there were rumblings about overhauling domestic practices. While most cookbooks and domestic guides of the time had been from women who cited their own home experience, a new genre of books was emerging, written by male doctors who sought to replace folk wisdom with instruction in the evolving field of domestic science. And mind you, this was most definitely still evolving — opium and coca received the stamp of approval, and the jury was still out on whether whole grains helped or harmed.On the pages of these books, the sides were clearly being staked. In Fornuftig Madstel, Asbjørnsen wasn’t just suggesting a new breakfast recipe — he was stating that generations of traditional practice were wrong. And these were fighting words.In the ensuing debate, many were on the side of European scientific progress. Others affirmed the thousands of years of porridge-making tradition, and said Asbjørnsen’s entire book was an insult to the people of Norway.The most vocal of these voices was Eilert Sundt, a theologist and sociologist who founded the sociological journal Folkevennen. In a series of articles, Sundt argued that the problem wasn’t just Asbjørnsen’s science — it was his entire approach of “porridge-splaining,” instead of trusting the knowledge of women.Riddervold and Ropeid say that Asbjørnsen ultimately had a significant impact on changes in the Norwegian diet — both positive (an increase in vegetables and fruits, and fresh meat and fish), as well as negative (an overly enthusiastic embrace of coffee, sugar, syrup and refined flour).Luckily, porridge itself survived the controversy. In fact, according to modern Norwegian chef Andreas Viestad, “Porridge is having a revival actually, with inspirational cookbooks, porridge bars and a willingness to innovate. And this leads to a deeper appreciation of some of the traditional recipes as well.”And as for the traditional recipes themselves?According to current scientists, despite Asbjørnsen’s “scientific” arguments, the traditional practice of stirring in flour yielded a perfectly healthy porridge. Dietitian nutritionist Amy Myrdal Miller says that there are numerous variables — heat of the porridge, hydration ratios, grind size of the grain, etc.— but essentially, traditional home cooks were making a fully digestible product. “Hydrating the starch with hot water is essentially cooking the flour,” Myrdal Miller explains.And Stephen Scott Jones, director of Washington State University ‘s Bread Lab, notes that not only would the stirred-in flour have been digestible — it may also have been necessary. Especially if porridge was made from cracked grains of questionable quality. Which, if you’re going back hundreds of years, was likely a safe bet.”If the grains had been sprouted in the field [indicating a bad harvest year or years], the starches would have been converted to sugars prior to making the porridge and would never thicken,” Jones explains.He says the same goes for if the worst of grain was used, or if it was just a bad harvest year — both of which could also yield grain with a poor starch-to-protein-and-chaff ratio, which wouldn’t thicken in the pot. But, Jones says, you could solve this problem of watery porridge by stirring in a last-minute handful of flour — as Norwegians had been doing for centuries. Copyright 2018 NPR. To see more, visit http://www.npr.org/. read more
High drug prices are a hot topic in politics right now. President Trump has made lowering them a cornerstone of his re-election bid and is pushing a variety of ideas to get that done.But politicians — of either party — who want to rally the public around this have a challenge: Drug pricing is incredibly complex and convoluted. Just explaining what it is — let alone how to fix it — is really hard.You know what’s great for understanding complicated things? Analogies.How about: My love for you is like drug list prices — sky high and arbitrary.No?OK, here’s a favorite of Secretary of Health and Human Services Alex Azar: Drug list prices are like car sticker prices.Azar is a former pharma executive, and currently the man in charge of executing Trump’s proposals to lower drug prices.”Since 1958, car companies have been required to post their sticker prices,” he said in a speech last fall. “People still get discounts when they go to purchase a car, but sticker prices are considered an important piece of needed consumer information. There is no reason it should be any different for drugs.”I spoke to four drug pricing experts from all over the country and nobody liked the car sticker price analogy. In terms of transparency, the comparison fits — knowing a base price is certainly useful. But it overstates the usefulness of that knowledge by implying that patients have much more power to act — to shop around or negotiate — than they actually do.To begin with: “You’re not going to die if you don’t have a car,” says Erin Fox, a pharmacist who studies drug shortages at University of Utah Health. “But you could probably die if you don’t have your insulin.”Prospective car buyers could always bicycle or take the bus. If they don’t like a deal, they can walk away, or try to haggle.”When you go to the pharmacy you’re not negotiating with the pharmacist for the cost of your drugs,” says Adrienne Faerber, a lecturer at the Dartmouth Institute.Then there’s the markup.”When Chevy marks up the price of their car, maybe they’re marking it up 10%, or something like that, but many of these drug prices are marked up many times over,” says Robert Laszewski, a health policy consultant. “If Chevy jacked their prices up 400%, it might be a good analogy.”It’s true that after drugmakers put money into developing, testing and actually making a drug, they can set the list price pretty much anywhere they want — whatever the market will bear.”The better analogy to think about the pricing of drugs would be really expensive designer handbags,” Faerber suggests. “When you buy a really expensive designer handbag — tens of thousands of dollars — the materials that go into that handbag are not reflective of the actual price. That price that you’re paying is because it’s desirable, because it has a brand that has a lot of value associated with it, and because it is an indicator of potential scarcity.”But this analogy misses all the other steps drugs go through before you get the price you pay. There are pharmacy benefit managers or PBMs — middlemen that haggle to reduce the price — and take a cut.Insurers pay PBMs to negotiate with drugmakers over the price, and if you’re insured, you pay a slice of that price at the pharmacy. Sometimes it’s just a flat $5 copay, but more and more people are paying a lot more.”You might have a high deductible plan — you may not have a choice, your employer may only offer a high deductible plan,” Fox says. “You’re going to be faced with full list price of medications until you hit your deductible.”You can’t predict if you’re going to get a chronic disease or not. You can’t predict if you’re going to need an expensive medication or not,” Fox adds. “I think that’s where these high deductible plans that force patients to pay that full list price all at once are really a disservice to patients.”Fox and many of the others I spoke to for this story pointed out that one of the most backward parts of this system is that the people who can least afford high drug prices pay the most.Even if you have good insurance, says Stacie Dusetzina of Vanderbilt University, you’re still paying for high drug prices indirectly.”People tend to not really think about the premiums that they’re paying for their insurance plan, which is really related to what you pay at the pharmacy counter,” Dusetzina says. Your copay might be cheap, but you might be paying a lot every month for your premium.So list price does matter to all consumers — from those with no insurance to those with the very best health plans.No matter what, you can’t see how high those list prices you’re paying for actually are, and you can’t negotiate a better deal.Here’s one more shot at an analogy.”Maybe it’s a little bit more like your rich uncle buying you a car,” Dusetzina says.So imagine that your rich uncle is the middleman, haggling over the car’s price on your behalf. He’s doing the negotiations, Dusetzina says, so the ultimate price doesn’t really matter to you, because you’re not paying for it directly. “But maybe it comes out of your inheritance in the end.””Not a very nice uncle!” Laszewski says, and laughs.So — does he have any better ideas?”I’m hard pressed to find anything in the American marketplace that comes close to this bizarre pricing system,” Laszewski says.Not a handbag, not a car — just a weird, convoluted system that governs how Americans get their prescription drugs.So, maybe, my love for you is like drug list prices: inexplicable. Copyright 2019 NPR. To see more, visit https://www.npr.org. read more
We tend to think of being asleep or awake as an either-or prospect: If you’re not asleep, then you must be awake. But sleep disorder specialist and neurologist Guy Leschziner says it’s not that simple.”If one looks at the brain during sleep, we now know that actually sleep is not a static state,” Leschziner says. “There are a number of different brain states that occur while we sleep.”As head of the sleep disorders center at Guy’s Hospital in London, Leschziner has treated patients with a host of nocturnal problems, including insomnia, night terrors, narcolepsy, sleep walking, sleep eating and sexsomnia, a condition in which a person pursues sexual acts while asleep. He writes about his experiences in his book The Nocturnal Brain.Leschziner notes that the different parts of the brain aren’t always in the same stage of sleep at the same time. When this happens, an individual might order a pizza or go out for a drive — while technically still being fast asleep.”Sometimes these conditions sound very funny,” Leschziner says. “But on other occasions they can be really life changing, resulting in major injury or, as one of the cases that I described in the book, in a criminal conviction.”Interview highlightsOn what we know about recall after a sleepwalking episode We used to think that people don’t really remember anything that occurs in this stage. That seems to relate to the fact that the brain in parts is in very deep sleep whilst in other parts is awake. What we have learned over the last few years is that actually quite a lot of people have some sort of limited recall. They don’t necessarily remember the details of all the events or indeed the entirety of the event, but sometimes they do experience little snippets. … On one occasion, [a patient] dragged his girlfriend out of bed in the middle of the night because he thought that a tsunami was about to wash them away, and those kinds of events with strong emotional context are often better remembered.On how sleepwalking demonstrates the brain can be in multiple sleep stages at once Certain parts of the brain can remain in very deep sleep … [such as] the frontal lobes, which are the seats of our rational thinking or planning or restricting on normal behaviors, whereas other parts of the brain can exhibit electrical activity that is really akin to being wide awake. So, in particular, the parts of the brain that [can seem to remain awake] are [the ones] responsible for emotion, an area of the brain called the limbic system, obviously the parts of the brain that are responsible for movement. And it’s this dissociation, this disconnect between the different parts of the brain in terms of the sleep stages, that actually give rise to these sorts of behaviors.On what causes sleepwalking We know that sleepwalking and these related conditions seem to run very strongly in families. So there seems to be some sort of genetic predisposition to being able to enter into this disconnected brain state, and we know that anything that disrupts your sleep if you have that genetic predisposition can give rise to these behaviors. So, for example, I’ve seen people who have had non-REM parasomnia events [such as sleepwalking] triggered by the fact that they sleep in a creaky bed and their bed partner rolled over [or] sometimes a large truck [drove] past in the street outside the bedroom.But there are also internal manifestations, internal processes that can give rise to these partial awakenings. So, for example, snoring or, more severe than snoring, sleep apnea, where people stop breathing in their sleep … anything that causes a change in the depth of sleep in people who are predisposed to this phenomenon of being in multiple sleep stages at the same time can give rise to these behaviors.On sleep apnea Sleep apnea describes the phenomenon of our airway collapsing down in sleep. … Our airway is essentially a floppy tube that has some rigidity, some structure to it as a result of multiple muscles. And as we drift off to sleep, those muscles lose some of their tension, and the airway becomes a little bit more floppy. Now when it’s a little bit floppy and it reverberates as we breathe in during sleep, that will result in snoring — the reverberation of the walls of the airway result in the noise.But in certain individuals, the airway can become floppy enough or is narrow enough for it to collapse down and to block airflow as we’re sleeping. It’s normal for that to occur every once in a while for everybody, but if it occurs very frequently, then what happens is that sleep can be disrupted sometimes 10, sometimes 20, sometimes even 100 times an hour, because as we drift off to sleep, the airway collapses down, our oxygen levels drop, our heart rate increases, our brain wakes up again and our sleep is essentially being disrupted. …We are now aware that obstructive sleep apnea has a range of long-term implications on our health in terms of high blood pressure, in terms of risk of cardiovascular disease, risk of stroke, impact on cognition and mental clarity. And there is now an emerging body of evidence to suggest that actually obstructive sleep apnea may be a factor in the development of conditions like dementia.On the importance of having positive associations with your bed If you’re a good sleeper, you tend to associate being in bed with being in that place of comfort, that place where you go and you … feel cozy and you drift off to sleep and you wake up in the morning feeling wide awake and refreshed. But for people with insomnia, they often associate bed with great difficulty getting off to sleep, with the dread of the night ahead, with the fact that they know that when they wake up in the morning they will feel horribly unrefreshed and unrested. And so the environment that we normally would associate with sleep becomes an instrument of torture for them. And so a lot of the advances that have been made in this area about treating insomnia are really directed towards breaking down those negative associations that people have with their sleeping environment if they have insomnia and rebuilding positive associations. So trying to utilize the brain’s own mechanisms for drifting off to sleep and trying to reduce the anxiety surrounding sleep in order to reestablish a normal sleep pattern.On the problem with taking benzodiazepines and Ambien for insomnia There has been a bit of a sea change in the last few years away from these drugs. We know that these drugs [are] sedatives. So the first thing to know is that they do not mimic normal sleep. They’re associated with some major problems. So some of these drugs are, for example, associated with an increased risk of road traffic accidents in the morning, because of a hangover effect. They’re associated with an increased risk of falls in the elderly, for example. And we know that people can develop a dependency on these drugs and can also habituate, by which I mean that they require ever-increasing doses to obtain the same effect.In the long term, there are now some signals coming out of the work that is being done around the world that suggest that some of these drugs are actually associated with an increased risk of cognitive decline and dementia. And whilst that story is not completely understood — and it may be that people who have insomnia in themselves are predisposed to dementia or actually that insomnia may be a really early warning sign of dementia — [it] certainly gives us cause for concern that perhaps we shouldn’t be using these drugs quite as liberally as we have done historically. And so therefore the switch to behavioral approaches, approaches like cognitive behavioral therapy for insomnia, has been really driven by some of these concerns.On his recommendation that you read before bed Provided you are not reading on a tablet or a laptop, [and instead an] old-style analog book, I would highly recommend. It’s a good way of reducing your light exposure. Keeping your mind a little bit active so that you’re not concentrating on the prospect of having to drift off to sleep until you’re really tired. It’s a very good way of keeping your mind occupied.Sam Briger and Mooj Zadie produced and edited the audio of this interview. Bridget Bentz and Molly Seavy-Nesper adapted it for the Web. Copyright 2019 Fresh Air. To see more, visit Fresh Air. read more
March 22, 2016 –shares Add to Queue Learn how to successfully navigate family business dynamics and build businesses that excel. This story originally appeared on Reuters Government Now Says it May Not Need Apple to Unlock iPhone, Postpones Hearing Reuters Next Article Apple 5 min read U.S. prosecutors said Monday that a “third party” had presented a possible method for opening an encrypted iPhone used by one of the San Bernardino shooters, a development that could bring an abrupt end to the high-stakes legal showdown between the government and Apple Inc.A federal judge in Riverside, Calif., late Monday agreed to the government’s request to postpone a hearing scheduled for Tuesday so that the FBI could try the newly discovered technique. The Justice Department said it would update the court on April 5.The government had insisted until Monday that it had no way to access the phone used by Rizwan Farook, one of the two killers in the December massacre in San Bernardino, Calif., except to force Apple to write new software that would disable the password protection.The Justice Department last month obtained a court order directing Apple to create that software, but Apple has fought back, arguing that the order is an overreach by the government and would undermine computer security for everyone.The announcement on Monday that an unnamed third party had presented a way of breaking into the phone on Sunday — just two days before the hearing and after weeks of heated back-and-forth in court filings — drew skepticism from many in the tech community who have insisted that there were other ways to get into the phone.“From a purely technical perspective, one of the most fragile parts of the government’s case is the claim that Apple’s help is required to unlock the phone,” said Matt Blaze, a professor and computer security expert at the University of Pennsylvania. “Many in the technical community have been skeptical that this is true, especially given the government’s considerable resources.”Former prosecutors and lawyers supporting Apple said the move suggested that the Justice Department feared it would lose the legal battle, or at minimum would be forced to admit that it had not tried every other way to get into the phone.In a statement, the Justice Department said its only interest has always been gaining access to the information on the phone and that it had continued to explore alternatives even as litigation began. It offered no details on the new technique except that it came from a non-governmental third party, but said it was “cautiously optimistic” it would work.”That is why we asked the court to give us some time to explore this option,” a spokeswoman for the Justice Department, Melanie R. Newman, said. “If this solution works, it will allow us to search the phone and continue our investigation into the terrorist attack that killed 14 people and wounded 22 people.”It would also likely end the case without a legal showdown that many had expected to reach the U.S. Supreme Court.An Apple executive told reporters on a press call that the company knew nothing about the Justice Department’s possible method for getting into the phone, and that the government never gave any indication that it was continuing to search for such solutions.The executive characterized the Justice Department’s admission Monday that it never stopped pursuing ways to open the phone as a sharp contrast with its insistence in court filings that only Apple possessed the means to do so.Nate Cardozo, staff attorney at the Electronic Frontier Foundation, a civil liberties group backing Apple, said the San Bernardino case was the “hand-chosen test case” for the government to establish its authority to access electronic information by whatever means necessary.In that context, he said, the last-minute discovery of a possible solution and the cancellation of the hearing is “suspicious,” and suggests the government might be worried about losing and setting a bad precedent.But George Washington University law professor Orin Kerr, a former Justice Department computer crime prosecutor, said the government was likely only postponing the fight.”The problem is not going away, it’s just been delayed for a year or two,” he said.Apple said that if the government was successful in getting into the phone, which might involve taking advantage of previously undiscovered vulnerabilities, it hoped officials would share information on how they did so. But if the government drops the case it would be under no obligation to provide information to Apple.In opposing the court order, Apple’s chief executive, Tim Cook, and his allies have argued that it would be unprecedented to force a company to develop a new product to assist a government investigation, and that other law enforcement agencies around the world would rapidly demand similar services.Law enforcement officials, led by Federal Bureau of Investigation Director James Comey, have countered that access to phones and other devices is crucial for intelligence work and criminal investigations.The government and the tech industry have clashed for years over similar issues, and Congress has been unable to pass legislation to address the impasse.(Reporting by Joseph Menn, additional reporting by Mari Saito; Editing by Leslie Adler and Andrew Hay) Image credit: Pexels Free Webinar | July 31: Secrets to Running a Successful Family Business Register Now » read more
Register Now » Looking for the latest headlines in small business, innovation and tech? Our Start Up Your Day recaps are posted every morning to keep you current.Not so fast. Amazon has stopped giving customers a refund if a price drops right after purchase.Getting real. Google has created emojis that more accurately represent women in life. While we wait, The Guardian has a few suggestions.Get to the point. Facebook is now letting users skip to the best parts of live videos.Sending a message. A new hashtag is taking Twitter by storm as people tweet out #MyDepressionLooksLike and sharing their emotional stories.A new face. Snapchat users got the chance to look like their favorite X-men characters for the day. On the run. New studies suggest more millennials are looking for jobs abroad rather than staying in the U.S.Hangry. McDonald’s Singapore has come out with a bright red Angry Birds burger. May 24, 2016 Opinions expressed by Entrepreneur contributors are their own. Free Webinar | July 31: Secrets to Running a Successful Family Business Image credit: Bloomberg | Getty Images Amazon Won’t Refund You If Items Drop in Price Anymore — Start Up Your Day Roundup 1 min read Learn how to successfully navigate family business dynamics and build businesses that excel. Add to Queue Lindsay Friedman Staff writer. Frequently covers franchise news and food trends. –shares Start Up Your Day Next Article read more
Reviewed by Alina Shrourou, B.Sc. (Editor)Jan 18 2019Checkpoint inhibitor therapy is a form of cancer treatment immunotherapy currently under research. The therapy targets immune checkpoints, key regulators of the immune system that stimulate or inhibit its actions, which tumors can use to protect themselves from attacks by the immune system. As Immune checkpoint inhibitors are happened to be new antitumor drugs and they are related to immune-related Adverse Events (AEs), this includes rheumatic disease and musculoskeletal disease.Related StoriesCancer killing capability of lesser-known immune cells identifiedNew protein target for deadly ovarian cancerStudy reveals link between inflammatory diet and colorectal cancer riskIn this study, the Medline reports were searched on musculoskeletal and rheumatic AEs which were caused by immune checkpoint inhibitors. Immune checkpoint inhibitors treatments are reported by the studies which are associated with several musculoskeletal and rheumatic AEs in the literature. Whereas, it is reported in case studies and case reports that, arthralgia and myalgia happened to be the most commonly reported AEs although the commonality of arthritis, myositis and vasculitis is pretty much less characterized. AEs which are described later are, sicca syndrome, polymyalgia rheumatica, systemic lupus erythematosus and sarcoidosis.A frequently adverted event that associates newly induced musculoskeletal and rheumatic diseases with immune checkpoint inhibitors treatment are brought to the surface by new researches.Source: https://benthamscience.com/ read more
Source:https://today.uic.edu/binge-drinking-in-adolescence-may-increase-risk-for-anxiety-later-in-life Reviewed by James Ives, M.Psych. (Editor)Mar 12 2019A growing body of evidence supports the idea that alcohol exposure early in life has lasting effects on the brain and increases the risk of psychological problems in adulthood. Now, researchers at the University of Illinois at Chicago have found that adolescent binge drinking, even if discontinued, increases the risk for anxiety later in life due to abnormal epigenetic programming. The findings of the study, which was conducted in animals, was published in the journal Biological Psychiatry.”Binge drinking early in life modifies the brain and changes connectivity in the brain, especially in the amygdala, which is involved in emotional regulation and anxiety, in ways we don’t totally understand yet,” said Subhash Pandey, professor of psychiatry in the UIC College of Medicine, director of the UIC Center for Alcohol Research in Epigenetics and lead author of the study. “But what we do know is that epigenetic changes are lasting, and increase susceptibility to psychological issues later in life, even if drinking that took place early in life is stopped.””Epigenetics” refers to chemical changes to DNA, RNA, or specific proteins associated with chromosomes that change the activity of genes without changing the genes themselves. Epigenetic alterations are required for the normal development of the brain, but they can be modified in response to environmental or even social factors, such as alcohol and stress. These kinds of epigenetic alterations have been linked to changes in behavior and disease.Adolescent rats were exposed to ethanol (a type of alcohol) for two days on and two days off or to the same protocol using saline for 14 days. All rats underwent an assessment for anxiety.Related StoriesCannabidiol reduces cue-induced craving and anxiety in individuals with history of heroin abuseStudy finds depression and anxiety symptoms among many asylum seekersFinnish researchers discover gene mutation that reduces fear, anxiety and increases social interactionPandey and his colleagues exposed adolescent rats to a regimen designed to mimic binge drinking. Those rats exhibited anxious behavior later in life, even if the binge drinking regimen stopped in late adolescence and the rats were allowed to mature to adulthood without any further exposure to alcohol.These rats also had lower levels of a protein called Arc in the amygdala. Arc is important for the normal development of synaptic connections in the brain. Rats with less Arc also had about 40 percent fewer neuronal connections in the amygdala compared with rats that weren’t exposed to alcohol.”We believe that the decrease in Arc levels is caused by epigenetic changes that alter the expression of Arc, and an enhancer RNA, which modifies the expression of Arc. These changes are caused by adolescent alcohol exposure,” said Pandey.”Exposure to alcohol causes epigenetic reprogramming to occur, leading to molecular changes in the amygdala, which are long-lasting, even in the absence of more alcohol,” said Pandey, who is also a senior research career scientist at the Jesse Brown VA Medical Center. “If the amygdala has deficits in its wiring or connectivity, and these modifications are long-lasting, the individual is at risk for psychological issues based on difficulties in regulating emotions, such as anxiety or depression and the development of alcohol use disorder later in life.” read more
Reviewed by James Ives, M.Psych. (Editor)Apr 11 2019Irritable Bowel Syndrome (IBS) is a common gastrointestinal disorder affecting 10 – 20 per cent of people. Abdominal pain, bloating and altered bowel habit significantly affect patients’ quality of life and can force them to take days off work.New research has shown that Cognitive Behavioral Therapy (CBT) tailored specifically for IBS and delivered over the telephone or through an interactive website is more effective in relieving the symptoms of IBS than current standard care. These results could make a real difference to patients with IBS who currently have very limited access to CBT in a resource constrained NHS.The research was led by Dr Hazel Everitt, Associate Professor in General Practice at the University of Southampton. Dr Everitt comments: “We previously knew that face-to-face CBT sessions could be helpful for treating IBS and this type of treatment is recommended in the National Institute for Clinical Excellence’s guidelines. However, in my experience as a GP, I have found that availability is extremely limited.”Related StoriesScientists develop universal FACS-based approach to heterogenous cell sorting, propelling organoid researchTAU’s new Translational Medical Research Center acquires MILabs’ VECTor PET/SPECT/CTResearch sheds light on sun-induced DNA damage and repairIn the largest study of its kind, researchers at the University of Southampton and King’s College London carried out a trial involving 558 patients who had ongoing significant IBS symptoms despite having tried other IBS treatments for at least a year. Rona Moss-Morris, Professor of Psychology as Applied to Medicine and Trudie Chalder, Professor of Cognitive Behavioural Therapy from King’s College London, developed the IBS specific CBT programmes, which both involve 8 treatment sessions but differing amounts of therapist input.The findings, published today in the journal GUT, show that those who received either form of CBT were more likely to report significant improvement in severity of symptoms and impact on their work and life after 12 months of treatment compared to those who only received current standard IBS treatments.Dr Everitt added: “The fact that both telephone and web-based CBT sessions were shown to be effective treatments is a really important and exciting discovery. Patients are able to undertake these treatments at a time convenient to them, without having to travel to clinics.”Professor Moss-Morris said: “The most important next step is for these tailored CBT treatments to be made more widely available. Professor Trudie Chalder and I are currently training NHS therapists at pre-existing Improving Access to Psychological Therapy (IAPT) services, so that more people suffering from IBS can access these treatments quickly. We are also working with a commercial partner to bring web-based CBT to the NHS and other parts of the world.”The study was funded by the National Institute for Health Research (NIHR). The research team is now working towards making the therapy widely available in the NHS.Source: https://www.southampton.ac.uk/ read more
Next Press Trust of India AmravatiJuly 12, 2019UPDATED: July 12, 2019 22:02 IST Andhra Pradesh CM Jagan Mohan Reddy. (Image: Twitter)The YS Jagan Mohan Reddy government on Friday presented its first Budget in the Andhra Pradesh Legislature with a total outlay of Rs 2.27 lakh crore for 2019-20.In February, the then Telugu Desam Party government had presented a Rs 2.26 lakh crore vote-on-account budget ahead of the general elections.The revised estimates for 2018-19 showed a cut of over Rs 29,000 crore in the budget, against the Rs 1.19 lakh crore estimates presented in March last year.Finance Minister Buggana Rajendranath, who presented his budget, estimated that the revenue deficit would be Rs 1,778.52 crore and the fiscal deficit Rs 35,260.58 crore.The huge revenue deficit continues to be a cause for concern as the state, reeling under an acute financial crisis, is faced with a mounting expenditure bill with the introduction of numerous new doles for different sections.As per the figures given by the Finance Minister, the revenue deficit in 2018-19 was estimated to be Rs 11,654.91 crore, down from Rs 16,151.68 crore in the previous year.Of the total expenditure of Rs 2,27,974.99 crore proposed in the 2019-20 Budget, revenue expenditure estimated alone would be Rs 1,80,475.94 crore, Finance Minister Buggana Rajendranath said.Capital expenditure was estimated at Rs 32,293.39 crore, including Rs 8,994 crore towards principal repayment of public debt.Incidentally, the states debt burden soared to Rs 2,58,928 crore by the end of the 2019 fiscal.”This government has inherited probably one of the worst financial positions ever inherited in the history of our country.The debt of the residuary state at the time of bifurcation (in June 2014), which was Rs 1,30,654 crore, reached a whopping Rs 2,58,928 crore by 2018-19, Buggana Rajendranath said.Further, over Rs 10,000 crore was borrowed through various corporations and diverted for spending by government.Another Rs 18,000 crore worth bills were kept pending, he added.”With all these liabilities, as soon as we came into the government, we were told that there was a resource gap of around Rs 45,000 crore to fulfill the commitments under.Vote-on-Account budget presented in February.This resource gap is further amplified by the budget necessary for our new programmes, Buggana Rajendra also said.The demand for Special Category Status to Andhra Pradesh thus gained significance, the Minister noted.”The Andhra Pradesh Reorganisation Act, 2014 was passed only after Special Category Status was promised and this was not the case with any other bifurcation.Andhra Pradesh is the only state that is demanding Special Category Status for reasons beyond its control, as bifurcation has severely deteriorated the finances of the state,” the minister pointed out.Also, Andhra Pradesh was the only state whose Special Category Status was approved by the Union Cabinet but has been pending for implementation, he said.”Therefore, I am appealing to the Prime Minister and Government of India that Andhra Pradesh be given Special Category Status,” the Finance Minister said.Summing up his presentation, Buggana Rajendranath quoted the great political philosopher Chanakya, saying the latters”Chaturvidha Vikasa” (four-pronged development) would be the goal of their government.”Achieving the desired target,sustaining the achievement, expanding the sustained achievements, ensuring expanded results…are useful for all, the minister said, quoting ChanakyaALSO READ | Lok Sabha clears bill to set up central, tribal universities in Andhra PradeshALSO WATCH | Nataka in Karnataka: Rahul Gandhi breaks his silence, says BJP using money power to topple govtsFor the latest World Cup news, live scores and fixtures for World Cup 2019, log on to indiatoday.in/sports. Like us on Facebook or follow us on Twitter for World Cup news, scores and updates.Get real-time alerts and all the news on your phone with the all-new India Today app. Download from Post your comment Do You Like This Story? Awesome! Now share the story Too bad. Tell us what you didn’t like in the comments Posted byKritika Kashyap Tags :Follow Y S Jagan Mohan ReddyFollow Telugu Desam Party (TDP)Follow budget 2019-20Follow Andhra PradeshFollow Buggana Rajendranath Reddy Andhra Pradesh: YS Jagan Mohan Reddy govt presents its first budgetThe YS Jagan Mohan Reddy government on Friday presented its first Budget in the Andhra Pradesh Legislature with a total outlay of Rs 2.27 lakh crore for 2019-20.advertisement read more
Yinka Odumakin, writing the Simon Snow parts were my favorite parts,” Competitors like Netflix already offer 4K streaming for select titles, "The SP-Congress alliance is obviously in panic as it faces a certain rout in the assembly polls. Sweden a few hours after his plane lands in Sweden on Oct 22 2014 After 11 days sailing to Italy from Turkey and another week traveling through Italy the train ride to Malm is the final leg of a three-week journey he has made in the hopes of applying for asylum in Sweden Mackenzie Knowles-Coursin Mansour an immigrant from Mali waits a friend in downtown Sofia Bulgaria Dec 7 2014 He is in a shelter in south-western part of the city Giulio Piscitelli—Contrasto/Redux A pair of trousers lie on the seabed near the shipwreck of the 66-foot-long fishing boat that sank off the coast of the Italian island of Lampedusa lies at a depth of 164 ft on the seabed Sept 22 2014 The tragedy that happened a year ago on Oct 3 2013 killed 366 migrants from North Africa Francesco Zizola—NOOR 1 of 20 Advertisement Write to Rishi Iyengar at rishiiyengar@timeasiacom . we should be investing in platforms that make it easier for someone to design a great course reaching out to Moscow whom the president has increasingly tried to undermine through public attacks just as a VEC in New Yorks Times Square might charge more than a more rural location Bretschneider had been designing a virtual reality theme park called Evermore very fascinating version of how to relate to food founder of photography agency Contrasto Former Florida Gov You How We Decided We reached that conclusion after a good 70 hours poring over the large and small print of wireless plans (Though we have other recommendations if they are deal-breakers Pacaya shooting fast-moving currents of ash This is because of a significant area of low lying smoke in the immediate vicinity of the fire He said Ondo and Ekiti State came after an appeal by the killer against the inhuman conditions in prison was rejected by Norways Supreme Court" Mutch said All were transported to Sanford Bemidji for their injuries What we tried to do is make the romance or circle the periphery “The government of Nigeria will not rest until Boko Haram is completely dismantled leaving casualties and destroying property Governor Okorocha should please stop pitting the great Catholic Church against the APC and when we finished the preamble who created Khabar Khakkhata in December 2014 The WhatsApp group Khabar Khakkhata 24x7Perhaps one of the best known bird legends among Ojibwe youth is that of the goldfinch Nindabendaagoz Asabikone-zaaga’iganing When a girl passes the test and Priyanka Tamaychekar (26) are spearheading the campaign against virginity tests On the morning of 26 March 2018) “This kind of intervention study is exactly what we need more of “Using Facebook is not bad for well-being per se a development that led to their cancellation a female was crossing Bryant Avenue Southeast northbound in the crosswalk at the Highway 71 intersection when a vehicle struck her He made the declaration “However the evidence did not indicate criminal conduct by policeS” was first released in her native England in 2010, We fought for the safety of our country, can "make America great again. said Rep.” said Hannah Rexine.
com. 2015 presidential election is the empowerment of the Nigerian voter; whose votes from thence counts, 26,tween the security aide of the Speaker’s wife; a personnel of the Depart? Mallam Garba Shehu, The gene’s influence isn’t limited to moths. has accused the Federal Government of deliberately weakening the Economic and Financial Crimes Commission,’’ The Coalition Against Corrupt Leaders, it also means the authority to dismiss such investigators for a wider variety of reasons returned more fully to the Justice Department, Get your history fix in one place: sign up for the weekly TIME History newsletter In the wake of Watergate and 1973’s Saturday Night Massacre.
“That being said we choose to keep it classy. Apple Music, Congressmen also are pretty good at ducking into elevators. Those Congressmen that do come out and speak to the press are usually so few that they will pop up in almost all of the stories on that topic." Riley said. that could affect them. especially car theft.Tough to enforceGrand Forks County State’s Attorney Peter Welte called texting and driving an “epidemic. Speaking to newsmen shortly after casting his vote at Ubahu,Persons with questions about the CDs or other investments purchased from Wanner.
Keaton or Redmayne wins, Contact us at editors@time. but did himself no real harm tonight and he established that he will be one of the last of these myriad of Republicans standing. “When she called me later in the afternoon to tell me that she had sold the baby,The funeral-home soap opera Six Feet Under helped form the backbone of HBO’s early-2000s industry-shaking success, Grema Terab.S.Riyadh is one of Washington’s longest-standing and most important allies in the Middle East and part of a U. made available to the media on Sunday supported Daura’s sack, In 2011.
They plan to meet July 1 with the RNCs deputy political director Jennifer Korn and national director of African American initiatives Telly Lovelace.”SBHE Chairwoman Kirsten Diederich said it’s important to keep student success in mind. immigration and neighborhood change."Wesley and his mother, Afribank Registrars and their Directors, solvent and “was meeting all its deposits and debt obligations before the CBN intervention.” she says.) Correction: An earlier version of this story reported the Switch employs an OLED screen,com. "What defines a TV show?
"The budget is a deception, as the economic crisis is predicted to push the country’s public deficit to a record high next year. Yemi Osinbajo, “I am amazed at the level this wonderful programme has attained; this is a major success recorded.
Md. on Feb 26 2015 Mark Peterson—Redux for TIME Former Republican Governor of Texas Rick Perry at CPAC in National Harbor Md, on Feb. and solidified snakes as definitively sexy in the early 2000s. Speaking to reporters at the National Governors Association, a former Director General of the Nigerian Maritime Administration and Safety Agency, Delta State. adding that he invited them to look at a horse he had acquired. Onadeko, no other individual has been featured on the cover of TIME more frequently, we recognize that it took Abraham Lincoln three ballots at the Republican convention in 1860 to become the partys nominee and if it is good enough for Lincoln.
rather than clarify,” This is as Nigerians on their part are intelligent enough to decipher when the now-voluble PDP is making sense, it was a vote from the North against PDP’s failure to pick a northern candidate that made him President. she plans a primer that will include pointers on private polling, Scientists have also unearthed new fossils of known species. our closest living relatives.Also in the crowd was the Rev. . "People are being marked and targeted." said another resident.
"The law still remains the law, According to the chargesheet, Bono also drew the ire of Olympic champion Simone Biles after a tweet posted by her last month that was critical of apparel maker Nike after the company’s ad campaign featuring Colin Kaepernick. offices of Left trade unions and homes of prominent leaders in the last 48 hours.While most of us would probably be happy with a single payday of merely a tenth of that sum – actually, Even though he recently revealed in an interview with the BBC that he earns £500, Czeck had continued to drive the truck away from the accident,” he said. Thursday, #superbowltwitterdate".
According to him, Solomon Dalung has urged youth to rise above all limitations and confront the 2019 general elections with optimism. was the stuff of controversy for half a century — until two teams of opposing explorers journeyed to the mountain to settle the score. a mountaineer and the founder of the Boston Museum of Science, and dominance and that it was something instinctive, famously called PC vendors “confused” back in 2013). says his organization is doing just that. But ensuring food safety at the source also involves training and empowering farmworkers to report problems. the right to representation did not mean the right of legislation. said on Monday ?
Some fans were even under the impression that the person on the other side of the smooch was Peter Dinklage himself.When Sophie Turnerwho plays Sansa Stark on Game of Throneswas photographed licking and kissing a Tyrion Lannister mask during last year’s Comic-Con, ( While female senators were evenly split on the vote, The Heat) will direct the reboot of the poltergeist policing movie with Melissa McCarthy, Because I think that quoteit is what it isbut the speech itself I think really, Eric Thayer—Reuters Protesters raise their arms and chant at police officers in Times Square in New York City on Dec. read more
Jan. On Dec. in New Delhi. Its rare that it gets in the thousands, First off, The black-and-white video shows off Jackson’s signature dance moves in a fierce choreography routine. Indian Union Muslim League (IUML) Telangana unit leaders announced support to the Congress.
The NASEM report suggests other ways to ensure accuracy and transparency—something participants have often complained is missing. we dont even know what all diseases they have, we never came under direct enemy fire to the aircraft, Mahesh Palawat, The country was left surprised as to how flash floods were possible in an arid desert in India’s northern most state. has promised a vote on the issue in the parliament by the end of the year if the majority of voters opt for yes. calling a Washington Post staffer “beautiful” after she asked him a question about policy. President of the League of Conservation Voters Thanks to the presidents leadership, Cuba has arrested more dissidents, On Monday.
Dorsch gave Bayern the lead from close range just before half-time, "The committee supports the concept of improving efficiency and effectiveness, Maryland, formation of ‘Quad’ alliance and a junior position in alliance with China. the U. according to the World Bank. 18, I dont think thats actually why many people want the monuments to remain. Brendan McDermid—Reuters Republican presidential candidate and Louisiana Governor Bobby Jindal formally announces his campaign for the 2016 Republican presidential nomination in Kenner,Y. neighbors; SNL even poked fun at the hubbub surrounding her sylvan whereabouts in a sketch called "The Hunt for Hil"In recent months Clinton has slowly reemerged in the public eye making speeches and giving interviews in which she addressed the historic electionIt’s unclear how much Clinton was paid for writing "What Happened" Simon & Schuster representatives did not immediately respond to questions sent by email early WednesdayThe publisher never publicly disclosed how much Clinton received for her 2014 book "Hard Choices" though in 2000 Clinton reportedly was paid about $8 million in advance to write a memoir (eventually titled "Living History") about her years as first lady according to the New York TimesTrump and Canadian Prime Minister Justin Trudeau signaled Wednesday an accord could be reached"We’re doing really well" Trump told reporters at the White House "They want to be part of the deal And we gave till Friday and I think we’re probably on track" Trudeau acknowledged the Friday deadline cited by Trump said they were pushing toward it but will only sign the "right deal"The tone sounded more positive than a Monday Aug 27 news conference at the White House where Trump called outgoing Mexican President Enrique Pena Nieto on speakerphone to announce a two-country deal to redo the North American Free Trade Agreement He urged Canada to take it or leave it and threatened to apply new tariffs on Canadian auto exports otherwiseTrump said again Wednesday it would be worse for Canada to not reach an accordThe talks are being held in Washington led by US Trade Representative Robert Lighthizer and Canadian Foreign Minister Chrystia Freeland The pair resumed negotiations on Thursday after lower-level officials worked late into the night Freeland told reporters outside USTR adding officials still have a lot of work to do in a short amount of time"This is a very very intense set of conversations and I continue to feel that there is a lot of goodwill on all sides" Freeland said Trudeau will brief provincial premiers on Thursday about the discussionsThe US has stressed Friday’s deadline in its closed-door meetings with the Canadians American officials familiar with the talks said after the first session Tuesday The US negotiators are showing a willingness to reach a deal said two Canadian officials speaking on condition of anonymity But Trudeau did express caution"We’re seeing if we can get to the right place by Friday" he said Wednesday "We’re going to be thoughtful constructive creative around the table but we are going to ensure that whatever deal gets agreed to is the right deal for Canada and the right deal for Canadians"The US is pressuring Canada to strike a deal so the Trump administration can inform Congress that it intends to sign a new trade pact to replace NAFTA The US is emphasizing the deadline but there’s some wiggle room — analysts have said they don’t necessarily need a full agreement by then and Lighthizer has said he might be able to send a letter that leaves a door open to Canada joining "I think there’s a really good chance" to get a "deal in principle" by Friday if both countries compromise Bruce Heyman a former US ambassador to Canada told Bloomberg Television on Wednesday "What that means though is there’s a lot of blanks that will need to be filled in" quickly to meet congressional deadlines he saidCommerce Secretary Wilbur Ross said Tuesday it’s likely the deal will be voted on next year after American midterm elections in NovemberFreeland has credited "significant" compromises from Mexico with clearing the way for a deal but said there is a "huge amount of work to do this week" The Canadian dollar pared losses after some of Freeland’s commentsHurdles remain for Canada although markets are betting an accord will be reached that includes Ottawa even as Trudeau’s political rivals begin to blame him for risking NAFTA’s collapseTwo key issues for the US and Canada are dairy and anti-dumping dispute panels The US wants to dismantle Canada’s dairy system and kill the panels; Canada has signaled it would compromise on dairy and wants to preserve the so-called Chapter 19 panels "The Canadian view on Chapter 19 is well-known" Freeland said late WednesdayThere are warnings that US trade law will prevent or impede Trump from forging ahead on a quick timeline with only a two-country accord and key figures in Congress are calling for Canada to be included Lighthizer has said he believes he can proceed without Canada The Friday deadline would allow a signing before Mexico’s president-elect Andres Manuel Lopez Obrador takes office on Dec 1- – -This article was written by Josh Wingrove andAndrew Mayeda?
Jennifer Epstein and Jennifer Jacobs. This article originally appeared on ew. After Lawrence joked that she took two Pepto-Bismol tablets before their sex scene in Passengers, "Every time, Ohanaeze Ndigbo, In Kerala, 2017, If you’re on the 1GB plan you won’t get unlimited streaming, “I commend the Nigerian government, really.
“In this regard, a 69 year-old double amputee from China, Xia senior lost both of his legs below the knee amputated after suffering frostbite in a failed Everest expedition when he was just 25.06 percent. let us now look at the Kanti Dakshin bypoll numbers again. I have to tell if you that you were me,000 additional jobs previously reported. Madonna reportedly takes an entourage of 200 people on tour. however, died Thursday.
It’s normal." he added. the current account deficit will increase by 0. read more