However, he told the group that the current level of antiviral resistance won’t necessarily persist, as sensitive flu strains might replace resistant ones. Osterholm also pointed out that antiviral resistance hasn’t been detected in influenza A/H3N2, a previous pandemic strain that is now a common seasonal strain. “It’s critical for businesses to understand how your states will use and distribute the antivirals,” he said. Osterholm warned viewers against releasing soon-to-expire antivirals for use in treating seasonal flu, because doing so might contribute to antiviral resistance. “The honest truth is no one knows,” said Osterholm, director of CIDRAP. During a question-and-answer session, some of the viewers said they struggled with shelf-life issues related to stockpiling, particularly during difficult economic conditions. Osterholm acknowledged that businesses and states are hamstrung by strict shelf-life rules, but he said stockpiling is still worth considering. Other companies offer turnkey solutions, which are online systems that register and educate employees and connect them with physicians who can write antiviral prescriptions, Quarry said. Turnkey systems offer the option of immediate distribution of the antivirals through mail order or pharmacies or traditional stockpiling. He said the limitations include paying for the drugs up front, renewing prescriptions each year, and keeping the stockpile current. Osterholm said according to the most recent information, there are 81 million antiviral treatment doses are in the Strategic National Stockpile (SNS) and state stockpiles. About 80% of the supply is oseltamivir (Tamiflu), and 20% is zanamivir (Relenza). Six million courses are to be used to help contain the pandemic outbreak, wherever it occurs in the world. Of the remaining courses, 50 million are in federal reserves and 25 million reside with states. Quarry advised businesses to optimize the potency of their stockpiles by regularly reviewing the storage conditions. “If you were heading down the antiviral path, who are the most important people in your plan?” he asked. “How you work that out might not necessarily be based on seniority.” He described a range of stockpiling options, which include antiviral reservation programs offered by Roche, the maker of Tamiflu, and GlaxoSmithKline, the producer of Relenza. The programs are typically less expensive than buying, rotating, and storing the drugs outright, he said. However, in the chaos of a pandemic, he said the two companies might still have problems distributing the antivirals to their corporate customers. Antiviral medications will still have a vital role to play, given that pandemic vaccine capacity will fall far short of the amount needed for the world population and that little is known about the efficacy of nonpharmaceutical interventions such as social distancing, he said. The drugs will allow employers to provide early treatment for employees who become ill or prophylaxis for workers who are critical to essential business operations. Jun 26, 2008, CIDRAP News story “Roche unveils plan to boost employer antiviral stockpiling” Doug Quarry, MBBS, MSc, medical director of International SOS Online, an international provider of medical assistance for travelers and corporate clients, told the group that once businesses factor antivirals into their pandemic plan, a key step is defining a stockpiling goal, which could range from a portion of employees to all employees and their dependents. “There is truly a real benefit for a company to control its own destiny,” he said, adding that businesses should be reluctant to dispose of expired antivirals, because shelf-life rules might change in a future emergency. At a webinar today sponsored by the Center for Infectious Disease Research and Policy (CIDRAP) Business Source, an online infectious-disease preparedness resource for businesses, Michael T. Osterholm, PhD, MPH, said experts can’t predict if high levels of antiviral resistance recently seen in seasonal influenza A/H1N1 viruses will have any bearing on treatment for a future pandemic strain. Mar 31, 2009 (CIDRAP News) Antiviral resistance and the global economic downturn might present new obstacles for corporate antiviral stockpiling, but two medical experts today said the medications are still quick, reliable tools that can help preserve business continuity in an influenza pandemic. See also: Sep 3, 2008, CIDRAP News story “Glaxo offers program to boost employer antiviral stockpiling” Quarry recommended that companies that have global offices assess the strengths of country pandemic and stockpiling plans, which vary widely. For example, stockpiling is difficult in China because prescriptions are valid for only 2 weeks. However, he added that locations such as Hong Kong and Germany have policies that make it easier for companies to stockpile antivirals.
Apr 9, 2009Vietnam receives avian flu support moneyVietnam yesterday received a $7.3 million pledge from the United Nations Food and Agriculture Organization (FAO) to support two avian influenza projects, Vietnam News Agency (VNA) reported today. The funds will be used to gather information for a transitional H5N1 vaccination strategy and to help Vietnam prepare for outbreaks.[Apr 9 VNA story]Ft Detrick biolab placed on Superfund listThe US Environmental Protection Agency (EPA) yesterday added a site on the US Army’s Ft Detrick, Md., biodefense facility to its Superfund National Priorities List, meaning officials will explore if contaminants at the site are having an impact on public health or the environment. The groundwater area placed on the list was used as a disposal site for chemical, biological, and radiological materials from the 1940s until 1970. Trichloroethene and tetrachloroethene has contaminated residential drinking water wells and could spread to areas in more densely populated Frederick, Md.[Apr 8 EPA press release]Stimulus money targets $300 million for immunizationIn announcing $2.3 billion in federal Recovery Act funds for health and human services programs today, Vice President Joe Biden said the Obama administration has targeted $300 million of the total for vaccines and grants to ensure that underserved Americans receive needed immunizations. The new resources will be used to buy vaccines for all 50 states, several large cities, and US territories. The vaccine funds will also cover immunization program operating costs and technical support, as well as vaccine awareness campaigns and innovative programs to boost childhood vaccination.[Apr 9 HHS press release]China announces plan to boost healthcare infrastructureThe Chinese government yesterday announced a major upgrade to its healthcare system, with a plan over the next 3 years to staff a clinic in each of its 700,000 villages, expand medical coverage to 90% of its people, build and renovate hospitals and clinics, and train 1.4 million healthcare workers, The Guardian, a British newspaper, reported. The central government said it would pay 40% of the costs, with local authorities to fund the remainder. Market reforms of the past decades have widened the medical coverage gaps between China’s rich and poor populations, and infectious disease issues such as SARS and avian influenza have focused global attention on the country’s healthcare system, the report said.[Apr 8 Guardian story] read more
Sep 17, 2009 (CIDRAP News) – A study in which N95 respirators strongly outperformed surgical masks in shielding hospital workers from influenza viruses and other microbes is being hailed as a landmark in research on respiratory protection for healthcare workers.The study, which involved close to 2,000 hospital staffers in Beijing, showed that N95 respirators reduced the risk of respiratory illness by a significant 60% and the risk of confirmed influenza by 75%, whereas surgical masks had no effect.The study was reported at an American Society for Microbiology meeting in San Francisco this week but has not yet been published in full form. It is described as the first randomized controlled trial comparing the effectiveness of N95 respirators and surgical masks.N95 respirators are designed to fit closely to the face and filter out 95% of airborne particles, whereas surgical masks are looser fitting and were originally designed to prevent the wearer from infecting others.But health workers say the tight-fitting N95s are uncomfortable and difficult to wear for long periods, and hospitals sometimes have trouble keeping them in supply. Surgical masks are more comfortable and cheaper, but scientists have not found much evidence that they protect wearers from respiratory pathogens.In the face of the H1N1 flu pandemic, respiratory protection for health workers has been a big issue. Two weeks ago, the National Academy of Sciences’ Institute of Medicine (IOM) issued a report affirming the current Centers for Disease Control and Prevention (CDC) guidance on the topic. The CDC recommends use of N95s by all healthcare workers who enter the rooms of patients with confirmed or suspected H1N1 infection. The same advice goes for emergency medical personnel who come in close contact with such patients.But the CDC is expected to issue some new guidance on the issue soon. CDC spokesman Tom Skinner said today that the new recommendations will be issued “by next week at the latest.”China chosen for good reasonThe IOM report said few studies have compared N95 respirators and surgical masks in clinical use. The new study, conducted by an international team led by Raina MacIntyre of the University of New South Wales in Australia, was designed to help fill that gap.The authors picked China as the study site because they wanted a place where hospital workers are used to wearing respiratory protection and thus would be likely to comply with the study protocol, MacIntyre told an IOM committee at a workshop in August. She said Asians are much more used to wearing face protection than their counterparts in the West.The researchers recruited 1,936 front-line workers at 24 Beijing hospitals, according to the study abstract from the Interscience Conference on Antimicrobials and Chemotherapy (ICAAC). They were assigned to one of four groups: surgical masks, fit-tested N95s, non-fit-tested N95s, or control (no respiratory protection). The volunteers wore their assigned form of protection for 4 weeks and were monitored for illness for 5 weeks.The authors found that surgical masks had no protective effect. In contrast, the N95s, compared with the controls, were linked with a 60% reduction in risk for any respiratory illness, a 75% reduction in flu-like illness, a 56% decrease in lab-confirmed respiratory illness, and a 75% reduction in confirmed flu, according to the report. The reductions met the test of statistical significance.However, the researchers found that fit-testing of the N95s—recommended by manufacturers to keep air from leaking around them—made no difference in protection.”These data are the first clinical data to confirm the superiority of N95 masks in preventing respiratory infections,” the authors state in their abstract. “Front line health workers are key to an effective pandemic response, and should be protected with N95 masks.”Concerning the finding that fit-testing doesn’t improve the effectiveness of N95s, they also say, “Given the logistic difficulties of fit testing, particularly during an infectious diseases emergency, this is an advantage for public health control.”Study wins praiseLisa Brosseau, a University of Minnesota researcher who has studied respiratory protection for years, agreed with the initial assessment by others, reported in the media, that the MacIntyre study is a major achievement in the field.”It is a landmark study,” she said. “I was very excited to hear it, because doing a clinical study comparing surgical masks and respirators is not an easy thing to do,” said Brosseau, an associate professor in the environmental sciences division of the university’s School of Public Health. “China is one of the only places where people would be willing to wear a respirator all the way through the day.””It’s hard to comment conclusively before reading the [full] paper, but based on her [MacIntyre’s] presentation and the data she’s given us, it’s a pretty clear conclusion that surgical masks do not offer protection, which is not very surprising based on the literature I’ve seen,” she said.Brosseau said that as the name suggests, surgical masks were originally designed to be worn by surgical teams to protect the surgical field from contamination. “But then they started being worn in many more settings,” encouraging an impression that they protect wearers, she said.MacIntyre’s study “illustrates how there is no protection from surgical masks, so I hope it’ll discourage people from saying there is protection,” Brosseau said.She said a few studies, particularly related to SARS (severe acute respiratory syndrome) in Asia and Canada, have seemed to show that surgical masks helped protect wearers from respiratory infections, but she called the findings questionable.”There’s a really big problem with retrospective studies,” she said. “How do you know that people really did wear those masks, and how much do you know about their exposure? Really in the end, what it’s arguing is that putting anything on your face is an improvement over putting nothing on your face.”As for the finding that fit-testing made no difference in benefits from the N95s, Brosseau suggested a possible explanation. She said MacIntyre told the IOM committee at the August workshop that her team used an N95 specially designed by 3M Co. for the Chinese face and that fewer than 5% of volunteers failed to pass the fit test. “Thus, this is a mask that is likely to fit most adults in the Chinese population very well, which is why fit testing did not make a significant difference in the rates of disease,” Brosseau said.MacIntyre C, Wang Q, Cauchemez S, et al. The first randomized, controlled clinical trial of surgical masks compared to fit-tested and non-fit-tested N95 masks in prevention of respiratory virus infection in hospital health care workers in Beijing, China. Presented Sep 15, 200, at ICAAC meeting, San Francisco (Abstract accessible through ICAAC meeting search page)See also: Sep 3 CIDRAP News story “IOM affirms CDC guidance on N95 use in H1N1 setting”Aug 12 CIDRAP News story “IOM hears diverse findings on PPE for flu” read more
“BIKING KRK – Feel good!” is a promotional campaign of the Tourist Board of the island of Krk intended for the development of cycling tourism on the island of Krk. For the fourth year in a row, in cooperation with all the island’s tourist boards, a number of both traditional and new cycling events have been promoted under a common name, with the aim of popularizing active holidays on the island of Krk.A series of seven bicycle races began with a joint active weekend in Omišalj and Malinska, followed in the coming weeks by weekend programs and cycling gatherings for all ages in Dobrinj, Baška, Krk, Dubašnica and Punat.Manifestacija „Biking Krk – Feels good“ pruža đirade po cijelom Krku, pritom spajajući lokalnu gastronomiju, tradiciju i doživljaj što je i smisao turizma. Brojni krčki ugostitelji pripremili su promotivne cijene proljetnih delicija poput krčke janjetine, šparoga i šurlica, uz tradicionalne zlatne kapljice vrbničke žlahtine.. Sve kroz zajedničku poruku Feel God. „The network of Krk promenades and bicycle paths is systematically arranged and marked, and today it covers an impressive 600 kilometers, and if those road routes are added to them, the number of kilometers available to cyclists is even higher. With the help of a new island cycling map, which unites all parts of Krk“They point out from TZO Krka.There is also a mobile app recently Krk Bike through which tourists can search for bicycle routes, from road, MTB and trekking, and where all the service and tourist information is. You can see the entire bicycle map of the island of Krk hereAn excellent tourist story and an example of how only joint efforts and merging tourist stories can create quality content and a complete tourist product. That is why it is important to brand one story, in this case the island of Krk, as a whole, and not for each city, ie the tourist community to develop and promote itself, without looking at the bigger picture. Guests do not see the borders we have set for ourselves, but see the island of Krk as a whole, as well as other tourist regions (Dalmatia, Istria, Slavonia, etc. ()Also, it is very important to complete the whole story with local tradition, gastronomy and cultural offer because that is the meaning of tourism, to offer a complete tourist product. read more
All Croatian tourism workers will unquestionably agree that the key to further “tourist success” of our country, whether we are talking about extending the season or increasing average earnings from tourism, is adequate investment in the development of tourism infrastructure, content and offer, in order to optimize money ”which, according to all research, is crucial for the choice of destination, ie further positive recommendations of satisfied guests. To this end, the Department for Market Research and Strategic Planning of the Croatian National Tourist Board has prepared an overview of direct flights and direct air connections of Croatian airports from 19 major emitting markets according to information obtained from Dubrovnik, Split, Zagreb, Zadar, Osijek, Pula, Mali Losinj. , Brač and Rijeka. More attached. Side dish: Overview of direct air connections of the Republic of Croatia – summer 2019 read more
Motor sailboat so-called. the three-masted schooner is 63,95 meters long, 10 meters wide and 5,35 meters high to the main deck. The 18 luxuriously equipped double cabins accommodate 36 passengers and are served by 9 crew members. The Croatian flag is flown on the sailing ship and has a class of passenger ships of unlimited navigation in all seas of the world, and during the domestic tourist season they will sail the Adriatic Sea, and the first passengers will be received on Saturday in Dubrovnik. It will also sail the coasts of Italy, Slovenia, Montenegro, Albania and Greece, and out of season in the Caribbean and other tourist destinations. The company is oriented towards projects and products that bring greater added value so that it has its own fleet of ships whose use, ie charter, complements the business. The handover of a motor yacht with three masts named ‘Klara’, contracted for its own shipping company Brodosplit-Plovidba doo, was just handed over today. DIV Group expands its business in the passenger cruise sector through the company DIV Cruises doo, owned by Brodosplit and which manages the fleet of ships as an agent for their use. Photo: Brodosplit “As a new shipping company, we want to promote the Croatian product and connect the domestic market. They would like to connect the whole of Croatia so that the menu offers excellent and original Croatian dishes and products. This is a unique business start-up in Croatia, and our vision is for DIV Cruises to offer the market a special, unique and different product with the local community. ” Tomislav Debeljak, President of the Management Board of Brodosplit, emphasized. In five years, over HRK 100 million has been invested in working capital and over HRK 400 million in its own fleet. read more
With this year’s slogan “Our glasses are not to be thrown away”, the Motovun Film Festival will encourage caterers to throw out glasses, straws and plastic spoons during the event. Those who join the action will be marked with a PLASTIC FREE certificate, and visitors will be invited to support such caterers. Disposable glasses that have been thrown away so far will be replaced by reusable glasses, which visitors will be able to return with a refund or keep as a souvenir. Their representatives will give a lecture In plastic shackles u Thursday, July 25 at 18:30 p.m. at the campground. It will discuss the harmful effects of plastics and especially microplastics on the environment and life in general, the extent of pollution with all future implications, and will offer solutions to prevent further pollution, as well as how each individual can actively participate in promoting rational and environmentally conscious use of plastic. Then, activist Marko Capek will use his own example to show how to completely eliminate plastic from his life, and he will also hold a workshop on making harmless deodorants and sun cubes. It is interesting how the collaboration came about. A simple calculation of last year’s edition of Motovun led to an interesting fact. The plastic cups that were used every day could be used to build a tower higher than the Motovun hill, which is located at a considerable 277 meters above sea level. Photo: Motovun Film Festival The partner of the festival is Greenpeace Croatia, whose representatives will hold a series of workshops and a lecture “In the shackles of plastic” Within two years, a ban on the use of disposable plastics will be incorporated into the laws of EU countries and the actions now being taken as almost a pioneering effort will become mandatory. RELATED NEWS: Motovun Film Festival, which takes place from July 23 to 27, joins the global action Plastic Free July with the aim of raising awareness about the harmfulness of disposable plastics, permanent environmental pollution and the consequences for living organisms. Also, in Saturday, July 27 at 18.30:XNUMX p.m. among Motovun campers comes Goran Zgrablić, a celebrated chef, sommelier and laser physicist who will hold a mini-course on cooking without waste, after which all participants in his workshop will participate in a jointly prepared feast! PLASTIC DISPOSABLE ITEMS FORBIDDEN IN 2021 EU FROM XNUMX read more